It's a really simple, powerful way of explaining a few differences that print based designers usually struggle with, like;
"in digital media we must make some compromises for the added factor of the way elements behave. Which is to say that, unlike the printed page, the components of a design — photos, illustrations, shapes, flourishes and type — can transform, change state, move, transform etc.".
Not only is it an important article, it's well written and it's easy to understand. Plus, Khoi is the Design Director of the wonderful New York Times online, so he knows a thing or two about grids.
If you're a designer who has designed mainly print all your life and you find websites a little bit, well, hard, then this is the article for you.
I'd like to know what you think about it.